Case Series: Successful Visual Recovery in Central Serous Chorioretinopathy with Spironolactone Treatment

 Purpose: To describe clinical outcomes of spironolactone therapy in patients with central serous chorioretinopathy (CSCR).  Methods: We present a case series of three male patients diagnosed with CSCR and treated with oral spironolactone 25 mg/day for three months. All patients underwent baseline and follow-up ophthalmologic evaluation, including uncorrected visual acuity (UCVA) and optical coherence tomography (OCT).  Results: All three patients showed significant anatomical and functional improvements. UCVA improved from 6/40 to 6/15 in Case 1, from 6/40 to 6/7.5 in Case 2, and from 6/40 to 6/8 in Case 3. OCT demonstrated near-complete resorption of subretinal fluid in all cases. No systemic or ocular adverse effects were reported during treatment.  Conclusion: Low-dose spironolactone was effective and well tolerated in CSCR, supporting its potential as a therapeutic option in both acute and persistent cases.

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Publication Details

Journal
International Journal of Scientific Research and Modern Technology.
Published
2025-09-26
DOI
https://doi.org/10.38124/ijsrmt.v4i9.821
Primary Topic
Retinal Diseases and Treatments
Type
article
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Case Series: Successful Visual Recovery in Central Serous Chorioretinopathy with Spironolactone Treatment

Maria Debora Niken Larasati, Ais Fricella, Yasin Fadillah
International Journal of Scientific Research and Modern Technology.
Retinal Diseases and Treatments
article

Case Series: Successful Visual Recovery in Central Serous Chorioretinopathy with Spironolactone Treatment

Maria Debora Niken Larasati, Ais Fricella, Yasin Fadillah
article en

Abstract

 Purpose: To describe clinical outcomes of spironolactone therapy in patients with central serous chorioretinopathy (CSCR).  Methods: We present a case series of three male patients diagnosed with CSCR and treated with oral spironolactone 25 mg/day for three months. All patients underwent baseline and follow-up ophthalmologic evaluation, including uncorrected visual acuity (UCVA) and optical coherence tomography (OCT).  Results: All three patients showed significant anatomical and functional improvements. UCVA improved from 6/40 to 6/15 in Case 1, from 6/40 to 6/7.5 in Case 2, and from 6/40 to 6/8 in Case 3. OCT demonstrated near-complete resorption of subretinal fluid in all cases. No systemic or ocular adverse effects were reported during treatment.  Conclusion: Low-dose spironolactone was effective and well tolerated in CSCR, supporting its potential as a therapeutic option in both acute and persistent cases.

International Journal of Scientific Research and Modern Technology.
Rumah Sakit Jantung Binawaluya (ID)
Openalex Percentile: Top 59%
Retinal Diseases and Treatments
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