Sensation kinetics identifies novel bladder sensation-capacity curve shapes during urodynamics in patients with urinary urgency
The key finding was the association between a j-shaped sensation-capacity curve, demonstrating a rapid acceleration of sensation near the end of filling, with both urgency symptom severity and bother. Curve shapes were not associated with bladder capacity or DO, suggesting that a j-shaped curve may potentially identify a separate driver of urinary urgency. Additional studies are needed to determine whether sensation-capacity curves can be used to identify novel OAB/urgency phenotypes or guide therapy.
Authors
- Nyasia M. Jones (ORCID: https://orcid.org/0000-0002-0764-7304)
- Adam P. Klausner (ORCID: https://orcid.org/0000-0003-3849-7131)
- Andrew Colhoun
- Zachary Cullingsworth (ORCID: https://orcid.org/0000-0002-4087-9764)
- Devina Thapa
- Anna S. Nagle (ORCID: https://orcid.org/0000-0001-9960-4864)
- Mrudula Bandaru
- John E. Speich (ORCID: https://orcid.org/0000-0002-8824-4098)
- Rui Li (ORCID: https://orcid.org/0000-0001-8353-6772)
- Aravindan Narayanan
Institutions
- Virginia Commonwealth University (US)
- Urology of Virginia (US)
Publication Details
- Journal
- Continence
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.cont.2025.102291
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00