Clonal origins and divergent evolutionary relationships of synchronous multiple malignant neoplasms in gynecology revealed by next-generation sequencing
Next-generation sequencing precisely resolved the diagnostic dilemma of gynecologic SMMNs by delineating an ovarian origin and a complex evolutionary pattern, thereby proving critical for guiding personalized treatment and screening strategies, particularly in hereditary cancer syndromes.
Authors
- Chunyan Liu (ORCID: https://orcid.org/0000-0002-3299-1115)
- Lu Sun (ORCID: https://orcid.org/0000-0001-6757-4955)
- Ruoyan Liu (ORCID: https://orcid.org/0000-0001-7874-6708)
- Jing Luan (ORCID: https://orcid.org/0000-0001-7064-4141)
- Jindong Sheng
- Yiwen Xing
- Wenxin Liu (ORCID: https://orcid.org/0000-0002-5733-1244)
- Wenfeng Cao (ORCID: https://orcid.org/0000-0001-6169-4577)
- Yujie Zhao (ORCID: https://orcid.org/0000-0002-6702-6526)
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Second Hospital of Tianjin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Cancer Treatment and Research Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.ctarc.2025.101013
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00