Poly-4-hydroxybutyrate mesh (GalaFlex®) in aesthetic breast surgery: A comprehensive systematic review

The P4HB mesh offers notable advantages, including high biocompatibility, long resorption time, and cost-effectiveness, making it a promising option for challenging cases in aesthetic breast surgery. It provides internal support for soft tissues and implants, especially where implant visibility is a concern. However, due to the variability in surgical procedures and the lack of robust evidence, solid conclusions about the optimal clinical use of P4HB meshes are still premature, necessitating further high-quality studies.

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Publication Details

Journal
JPRAS Open
Published
2025-10-04
DOI
https://doi.org/10.1016/j.jpra.2025.09.029
Citations
1
Primary Topic
Breast Implant and Reconstruction
Type
article
Field-Weighted Citation Impact
2.01
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article

Poly-4-hydroxybutyrate mesh (GalaFlex®) in aesthetic breast surgery: A comprehensive systematic review

G Cervelli, Mario Alessandri‐Bonetti, Carlo Cossi, Bong‐Sung Kim et al.
1 citations
JPRAS Open
Breast Implant and Reconstruction
2.01
article

Poly-4-hydroxybutyrate mesh (GalaFlex®) in aesthetic breast surgery: A comprehensive systematic review

G Cervelli, Mario Alessandri‐Bonetti, Carlo Cossi, Bong‐Sung Kim, Gabriele Storti, Valerio Cervelli, Marco Palmesano, Andrea Lisa, Riccardo Foti, Irene Nunziata
article en
1 citations

Abstract

The P4HB mesh offers notable advantages, including high biocompatibility, long resorption time, and cost-effectiveness, making it a promising option for challenging cases in aesthetic breast surgery. It provides internal support for soft tissues and implants, especially where implant visibility is a concern. However, due to the variability in surgical procedures and the lack of robust evidence, solid conclusions about the optimal clinical use of P4HB meshes are still premature, necessitating further high-quality studies.

JPRAS OpenVol. 46
University of Rome Tor Vergata (IT), Humanitas University (IT), University of Milan (IT), University Hospital of Zurich (CH)
Openalex Percentile: Top 11%
Breast Implant and Reconstruction
2.01
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Poly-4-hydroxybutyrate mesh (GalaFlex®) in aesthetic breast surgery: A comprehensive systematic review — G Cervelli, Mario Alessandri‐Bonetti, et al. · JPRAS Open (2025) | TGRS Research Map | TGRS