Novel Molecular Subtyping Predicts Locoregional Recurrence in Triple-negative Breast Cancer

This study demonstrated that the BLIS subtype appears to be at a higher risk of developing LRR, and IHC-based molecular subtyping might be used as prognostic biomarkers to guide postmastectomy radiation therapy in patients with TNBC. New strategies that improve locoregional control rates in patients with BLIS are warranted.

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Publication Details

Journal
Advances in Radiation Oncology
Published
2025-10-04
DOI
https://doi.org/10.1016/j.adro.2025.101909
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
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article

Novel Molecular Subtyping Predicts Locoregional Recurrence in Triple-negative Breast Cancer

Zhaozhi Yang, Xiaoli Yu, Shali Shao, Zhen Zhang et al.
Advances in Radiation Oncology
Breast Cancer Treatment Studies
article

Novel Molecular Subtyping Predicts Locoregional Recurrence in Triple-negative Breast Cancer

Zhaozhi Yang, Xiaoli Yu, Shali Shao, Zhen Zhang, Li Zhang, Xiaomao Guo, Qixian Zhang, Jin Meng, Miao Mo, Wei Shi
article en

Abstract

This study demonstrated that the BLIS subtype appears to be at a higher risk of developing LRR, and IHC-based molecular subtyping might be used as prognostic biomarkers to guide postmastectomy radiation therapy in patients with TNBC. New strategies that improve locoregional control rates in patients with BLIS are warranted.

Advances in Radiation OncologyVol. 10(12)
Shanghai Medical College of Fudan University (CN), Fudan University Shanghai Cancer Center (CN), Women's Hospital, School of Medicine, Zhejiang University (CN), Shanghai Institute of Hematology (CN), Shanghai Clinical Research Center (CN)
Openalex Percentile: Top 66%
Breast Cancer Treatment Studies
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Novel Molecular Subtyping Predicts Locoregional Recurrence in Triple-negative Breast Cancer — Zhaozhi Yang, Xiaoli Yu, et al. · Advances in Radiation Oncology (2025) | TGRS Research Map | TGRS