TERT expression attenuates metabolic disorders in obese mice by promoting adipose stem and progenitor cell expansion and differentiation
These results underscore TERT's role in mitigating obesity-related metabolic dysfunction. Conditional TERT expression may therefore represent as a promising therapeutic strategy for obesity-associated metabolic disorders.
Authors
- Antonio M. A. Miranda (ORCID: https://orcid.org/0000-0003-4281-614X)
- Frédéric Jourquin (ORCID: https://orcid.org/0000-0001-6848-6973)
- Jesús Gil (ORCID: https://orcid.org/0000-0002-4303-6260)
- Julien Vernerey (ORCID: https://orcid.org/0000-0002-5413-4210)
- Laura Braud (ORCID: https://orcid.org/0000-0002-8958-3817)
- Vincent Géli (ORCID: https://orcid.org/0000-0002-4103-7462)
- Christophe Lachaud (ORCID: https://orcid.org/0000-0003-2762-1619)
- Liam McAllan (ORCID: https://orcid.org/0000-0002-6215-4289)
- Dmitri Churikov (ORCID: https://orcid.org/0000-0003-1127-8852)
- W Scott
- Andrea Domínguez
- Manon Richaud (ORCID: https://orcid.org/0009-0001-7807-9770)
- Manuel Bernabé
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut de Recherche sur le Cancer et le Vieillissement de Nice (FR)
- Centre de Recherche en Cancérologie de Marseille (FR)
- MRC London Institute of Medical Sciences (GB)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.molmet.2025.102262
- Citations
- 2
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.71