A liberalized approach to directly observed therapy for HCV retains excellent cure rates among PWID in Vienna
DOT originally aimed to address non-adherence among PWID by strict control through daily supervised OAT and DAA ingestion. While this approach inherently manifests a position of advanced distrust towards PWID, our findings suggest that a strategy of advanced trust and liberalization of DOT alongside effective harm reduction measures yields excellent adherence and results in similarly high HCV cure rates.
Authors
- David Bauer (ORCID: https://orcid.org/0000-0002-9363-8518)
- Michael Schwarz (ORCID: https://orcid.org/0000-0002-2587-1385)
- Michael Gschwantler
- Caroline Schwarz (ORCID: https://orcid.org/0000-0001-7762-7483)
- Angelika Schütz
- L Burghart
- E Gutic
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- Maximilian Anibas
Institutions
- Sigmund Freud Privatuniversität Wien (AT)
- University of Applied Sciences St Pölten (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Journal of Virus Eradication
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.jve.2025.100611
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00