Overview of Ketamine Guidelines in Psychiatric Disorders

Ketamine has anti depressive characters and approved by (FDA) for the induction and maintenance of anesthesia, Ketamine has been incorporated into the management of psychiatric disorders, such as Major Depressive Disorder (MDD) especially with suicidal ideation or attempting, and of label in management of Bipolar Disorder, Post-Traumatic Stress Disorder (PTSD), Obsessive-Compulsive Disorder (OCD), Substance Use Disorders (SUD).Intravenous ketamine regimen is not a first-line management for psychiatric disorders and considered by the patient’s interdisciplinary team work after failure of standard treatment. Ketamine mechanism of action is different from existing treatments and has demonstrated efficacy in improving people with Major Depression Disorder where conventional first line management as antidepressants, psychotherapy, have not be fully effective. In this paper we discussed all aspects of ketamine Protocol and guidelines usages in psychiatric.

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Publication Details

Journal
International Journal of Psychiatry
Published
2025-09-26
DOI
https://doi.org/10.33140/ijp.10.03.04
Primary Topic
Treatment of Major Depression
Type
article
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article

Overview of Ketamine Guidelines in Psychiatric Disorders

Hesham Maged Mohamed Abdelfatah, Mahmoud Mohamed Gomaa
International Journal of Psychiatry
Treatment of Major Depression
article

Overview of Ketamine Guidelines in Psychiatric Disorders

Hesham Maged Mohamed Abdelfatah, Mahmoud Mohamed Gomaa
article en

Abstract

Ketamine has anti depressive characters and approved by (FDA) for the induction and maintenance of anesthesia, Ketamine has been incorporated into the management of psychiatric disorders, such as Major Depressive Disorder (MDD) especially with suicidal ideation or attempting, and of label in management of Bipolar Disorder, Post-Traumatic Stress Disorder (PTSD), Obsessive-Compulsive Disorder (OCD), Substance Use Disorders (SUD).Intravenous ketamine regimen is not a first-line management for psychiatric disorders and considered by the patient’s interdisciplinary team work after failure of standard treatment. Ketamine mechanism of action is different from existing treatments and has demonstrated efficacy in improving people with Major Depression Disorder where conventional first line management as antidepressants, psychotherapy, have not be fully effective. In this paper we discussed all aspects of ketamine Protocol and guidelines usages in psychiatric.

International Journal of PsychiatryVol. 10(03)
Openalex Percentile: Top 69%
Treatment of Major Depression
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