B7-H3 in Colorectal Adenocarcinoma: Are We Focusing on the Right Target?
The presented data provide further evidence on the role of B7-H3 in CRC with particular reference to the tumor microenvironment and histotype, with a possible implication for the CRC therapy. Further studies are required to both confirm these data and elucidate the role of B7-H3 as a potential target to unleash the response to immunotherapy in CRC.
Authors
- Valentina Angerilli (ORCID: https://orcid.org/0000-0002-9799-9257)
- Paola Parente (ORCID: https://orcid.org/0000-0003-0591-6723)
- Matteo Fassan (ORCID: https://orcid.org/0000-0001-6515-5482)
- Davide Ciardiello (ORCID: https://orcid.org/0000-0003-1826-0305)
- Jessica Gasparello (ORCID: https://orcid.org/0000-0001-8557-0739)
Institutions
- University of Padua (IT)
- Casa Sollievo della Sofferenza (IT)
- AULSS 2 Marca Trevigiana (IT)
- Istituto Oncologico Veneto (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- European Institute of Oncology (IT)
Publication Details
- Journal
- Clinical Colorectal Cancer
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.clcc.2025.09.005
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00