Longitudinal changes in late-life brain health after prenatal exposure to the Dutch famine
Our results support prenatal famine exposure affecting brain structure and perfusion across the lifespan. The absence of group differences in rate of change over time supports a hypothesis of persistent developmental effects rather than accelerated brain aging after prenatal famine exposure.
Authors
- Anouk Schrantee (ORCID: https://orcid.org/0000-0002-4035-4845)
- Luigi Lorenzini (ORCID: https://orcid.org/0000-0002-9756-881X)
- Aline Marileen Wiegersma (ORCID: https://orcid.org/0000-0002-6856-9776)
- Henk J. M. M. Mutsaerts (ORCID: https://orcid.org/0000-0003-0894-0307)
- Amber Boots (ORCID: https://orcid.org/0000-0002-8469-7006)
- Tessa J. Roseboom (ORCID: https://orcid.org/0000-0003-0564-5994)
- Beatriz Padrela (ORCID: https://orcid.org/0000-0001-6836-9443)
- Susanne R. de Rooij (ORCID: https://orcid.org/0000-0001-7382-5749)
- Jessica S. Damoiseaux (ORCID: https://orcid.org/0000-0003-2312-7728)
Institutions
- Wayne State University (US)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121505
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek