Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough
Our findings highlighted the clinical potential of Keke Tablet in the treatment of post-infectious cough, and confirmed that Keke tablet improved cough symptoms by alleviating inflammatory response. MAPK/NF-κB signaling pathway is one of the potential pathways of Keke tablet in the treatment of post-infectious cough.
Authors
- Jiahe Zhang
- Weixuan Chen
- Weiwei Qiao (ORCID: https://orcid.org/0000-0002-8816-9198)
- Hua Zhou
- Li‐Hua Peng (ORCID: https://orcid.org/0000-0001-9763-383X)
- Peng Sun (ORCID: https://orcid.org/0000-0003-4117-4165)
- Yu Feng
- Minling Lai (ORCID: https://orcid.org/0000-0002-4553-7552)
- Mengyue Su
- Yanling Liang
- Shukun Wang
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shandong University of Traditional Chinese Medicine (CN)
- Zhongshan People's Hospital (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1186/s13020-025-01199-7
- Primary Topic
- Respiratory and Cough-Related Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00