Management of peripheral-vein leiomyosarcomas, recurrence patterns and individualised treatment strategy
Peripheral vein LMS demonstrates a low local recurrence but high metastatic risk. Radiotherapy did not significantly impact local control, and it was typically utilized in higher-grade, deep-seated tumours that carry a greater risk of local relapse. These findings suggest that in peripheral vein LMS, systemic risk outweighs local control benefits from RT, highlighting the need for individualised treatment strategies and further prospective studies.
Authors
- Charlotte Benson (ORCID: https://orcid.org/0000-0002-3241-3630)
- Myles Smith (ORCID: https://orcid.org/0000-0002-3254-4817)
- Khin Thway (ORCID: https://orcid.org/0000-0001-9727-8030)
- Robin L. Jones (ORCID: https://orcid.org/0000-0003-4173-3844)
- D. Strauß (ORCID: https://orcid.org/0000-0003-2413-0697)
- Aisha Miah (ORCID: https://orcid.org/0000-0001-6946-0820)
- Jens Strohäker (ORCID: https://orcid.org/0000-0001-7397-3389)
- Andrew Hayes (ORCID: https://orcid.org/0000-0002-9832-4219)
- Shane Zaidi
Institutions
- Royal Marsden NHS Foundation Trust (GB)
- Royal Marsden Hospital (GB)
- University of Tübingen (DE)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-10-04
- DOI
- https://doi.org/10.1016/j.ejso.2025.110448
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00