EP13.03 AN EVALUATION OF SHORT-TERM OUTCOMES AND FOLLOW-UP SCHEDULES AFTER MENINGIOMA SURGERY

Abstract BACKGROUND Heterogeneity exists between neurosurgical centres and individual surgeons regarding schedules of clinic follow-up and imaging after meningioma surgery, driven in part by resource constraints. We aimed to evaluate short-term (1-2 year) post-surgical functional outcomes, focusing on the effects of surgical results, post-operative complications and follow-up. MATERIAL AND METHODS A retrospective cohort study of 146 patients (mean age 60.2 ± 15 years, 77% female) who underwent craniotomy for meningioma resection between April 2020 and March 2022 at a single tertiary centre was conducted. Operative records and patient charts were reviewed for demographics, tumour features, Simpson Grade, complications, functional outcomes and follow-up schedule. Multivariate regression was used to assess the relative importance of patient characteristics and provider factors in recovery. RESULTS Most patients were symptomatic preoperatively (92.5%), commonly with focal deficits (29.5%) and seizures (26.7%). The mean tumour diameter was 41.8±16.1mm, with 76.7% WHO Grade 1. Simpson Grade 1 or 2 resection was achieved in 84.2% of cases. Post-operative complications within 30 days occurred in 41.1%, including new or worsened focal deficits in 15.8%, seizures in 9.6% and infection in 3.4%. In 52.7% of cases, patients were discharged in ≤4 days. Functional status improved significantly, with mean mRS scores decreasing from 2.1 pre-surgery to 1.8 at one year and 1.4 at two years (p < 0.05). Considering follow-up, 47.3%, 84.9%, and 95.9% of patients were reviewed in clinic within one, three, and six months, respectively. The first surveillance MRI occurred at a mean of 4.7 months, with 66.4% completed within five months. Timely imaging and clinic review correlated with improved functional recovery in multivariate analyses (p = 0.006 and 0.037 respectively). Advanced age, multifocal tumours, and complications within 30 days were also significant predictors of adverse outcomes. CONCLUSION Meningioma surgery is associated with substantial functional improvement. Early and structured follow-up, including timely imaging, is a significant factor in uncomplicated recovery. A consistent set of outcome measures is helpful for understanding surgical outcomes across cohorts.

Authors

Institutions

Publication Details

Journal
Neuro-Oncology
Published
2025-10-01
DOI
https://doi.org/10.1093/neuonc/noaf193.629
Primary Topic
Meningioma and schwannoma management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

EP13.03 AN EVALUATION OF SHORT-TERM OUTCOMES AND FOLLOW-UP SCHEDULES AFTER MENINGIOMA SURGERY

Rahul Shah, Alexis Joannides, Tamara Tajsic
Neuro-Oncology
Meningioma and schwannoma management
article

EP13.03 AN EVALUATION OF SHORT-TERM OUTCOMES AND FOLLOW-UP SCHEDULES AFTER MENINGIOMA SURGERY

Rahul Shah, Alexis Joannides, Tamara Tajsic
article en

Abstract

Abstract BACKGROUND Heterogeneity exists between neurosurgical centres and individual surgeons regarding schedules of clinic follow-up and imaging after meningioma surgery, driven in part by resource constraints. We aimed to evaluate short-term (1-2 year) post-surgical functional outcomes, focusing on the effects of surgical results, post-operative complications and follow-up. MATERIAL AND METHODS A retrospective cohort study of 146 patients (mean age 60.2 ± 15 years, 77% female) who underwent craniotomy for meningioma resection between April 2020 and March 2022 at a single tertiary centre was conducted. Operative records and patient charts were reviewed for demographics, tumour features, Simpson Grade, complications, functional outcomes and follow-up schedule. Multivariate regression was used to assess the relative importance of patient characteristics and provider factors in recovery. RESULTS Most patients were symptomatic preoperatively (92.5%), commonly with focal deficits (29.5%) and seizures (26.7%). The mean tumour diameter was 41.8±16.1mm, with 76.7% WHO Grade 1. Simpson Grade 1 or 2 resection was achieved in 84.2% of cases. Post-operative complications within 30 days occurred in 41.1%, including new or worsened focal deficits in 15.8%, seizures in 9.6% and infection in 3.4%. In 52.7% of cases, patients were discharged in ≤4 days. Functional status improved significantly, with mean mRS scores decreasing from 2.1 pre-surgery to 1.8 at one year and 1.4 at two years (p < 0.05). Considering follow-up, 47.3%, 84.9%, and 95.9% of patients were reviewed in clinic within one, three, and six months, respectively. The first surveillance MRI occurred at a mean of 4.7 months, with 66.4% completed within five months. Timely imaging and clinic review correlated with improved functional recovery in multivariate analyses (p = 0.006 and 0.037 respectively). Advanced age, multifocal tumours, and complications within 30 days were also significant predictors of adverse outcomes. CONCLUSION Meningioma surgery is associated with substantial functional improvement. Early and structured follow-up, including timely imaging, is a significant factor in uncomplicated recovery. A consistent set of outcome measures is helpful for understanding surgical outcomes across cohorts.

Neuro-OncologyVol. 27(Supplement_3)
University of Cambridge (GB), Cambridge University Hospitals NHS Foundation Trust (GB)
Openalex Percentile: Top 63%
Meningioma and schwannoma management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.