Eplerenone improves kidney function and cardiac performance in obese male mice
Eplerenone treatment improved kidney function and cardiac performance in obese male mice. The potential link between the mineralocorticoid receptor and the hyaluronan-CD44/RHAMM pathway is novel and has not been previously reported.
Authors
- Ryan G. L. Koh
- Tianzhen Wang (ORCID: https://orcid.org/0000-0002-7525-8466)
- Bingxue Qi (ORCID: https://orcid.org/0009-0007-8660-1569)
- Colin E. Murdoch (ORCID: https://orcid.org/0000-0002-0274-819X)
- Vishal Musale (ORCID: https://orcid.org/0000-0002-8760-4637)
- Jill Rachel Mains (ORCID: https://orcid.org/0000-0002-3185-7053)
- Ayman K. Banah (ORCID: https://orcid.org/0009-0009-4951-8445)
- Li Kang (ORCID: https://orcid.org/0000-0002-6990-1996)
- Alexander Lawlor
Institutions
- University of Dundee (GB)
- Umm al-Qura University (SA)
- People 's Hospital of Jilin Province (CN)
Publication Details
- Journal
- Diabetic Medicine
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1111/dme.70154
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- British Heart Foundation
- Diabetes UK
- China Scholarship Council
- Umm Al-Qura University