Evaluation of the antidiarrheal activity of dichloromethane-methanol crude extract of the aerial parts of Croton kinondoensis (Euphorbiaceae) in Mice

C. kinondoensis exhibits dose-dependent antidiarrheal and antimotility effects, supporting its traditional use. Although its efficacy was lower than loperamide, the extract demonstrated significant potential as a natural remedy for diarrhea.

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Publication Details

Journal
PLoS ONE
Published
2025-10-03
DOI
https://doi.org/10.1371/journal.pone.0333527
Citations
1
Primary Topic
Ethnobotanical and Medicinal Plants Studies
Type
article
Field-Weighted Citation Impact
1.75
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article

Evaluation of the antidiarrheal activity of dichloromethane-methanol crude extract of the aerial parts of Croton kinondoensis (Euphorbiaceae) in Mice

Ermias Mergia Terefe, Abdullahi Ibrahim Osman Noor
1 citations
PLoS ONE
Ethnobotanical and Medicinal Plants Studies
1.75
article

Evaluation of the antidiarrheal activity of dichloromethane-methanol crude extract of the aerial parts of Croton kinondoensis (Euphorbiaceae) in Mice

Ermias Mergia Terefe, Abdullahi Ibrahim Osman Noor
article en
1 citations

Abstract

C. kinondoensis exhibits dose-dependent antidiarrheal and antimotility effects, supporting its traditional use. Although its efficacy was lower than loperamide, the extract demonstrated significant potential as a natural remedy for diarrhea.

PLoS ONEVol. 20(10)
Africa International University (KE), United States International University Africa (KE)
Openalex Percentile: Top 12%
Ethnobotanical and Medicinal Plants Studies
1.75
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