T cell subsets of urine-derived lymphocytes (UDLs) serve as an indicator of TILs and reflect immunological sex differences in bladder cancer
Assessment of UDLs opens avenues of non-invasive biomarker development in clinical settings where bladder cancer TILs are hypothesized to predict clinical response. UDLs may also reflect sex-based differences in antitumor immunity.
Authors
- Zihai Li (ORCID: https://orcid.org/0000-0003-4603-927X)
- Kyeong Joo Jung (ORCID: https://orcid.org/0000-0002-0582-1583)
- Steven K. Clinton (ORCID: https://orcid.org/0000-0002-2840-5865)
- No‐Joon Song (ORCID: https://orcid.org/0009-0002-0947-0597)
- Vincent M. Caruso (ORCID: https://orcid.org/0000-0002-8738-2552)
- Debasish Sundi (ORCID: https://orcid.org/0000-0001-6980-4777)
- Krishan Kumar (ORCID: https://orcid.org/0000-0003-4406-2644)
- Cheryl T. Lee
- Hyeongseon Jeon (ORCID: https://orcid.org/0000-0002-3539-4332)
- Kamal S. Pohar (ORCID: https://orcid.org/0000-0001-8461-4584)
- Timothy D. Gauntner (ORCID: https://orcid.org/0000-0002-4745-2130)
- Trevor G. Levin (ORCID: https://orcid.org/0000-0003-1323-1126)
- David J. McConkey (ORCID: https://orcid.org/0000-0003-1971-0638)
- William Edgar Carson (ORCID: https://orcid.org/0000-0001-7024-7533)
- Tong Xiao (ORCID: https://orcid.org/0000-0002-2130-2281)
- Dongjun Chung (ORCID: https://orcid.org/0000-0002-8072-5671)
- Kelsi Reynolds (ORCID: https://orcid.org/0009-0001-8201-7644)
- Johanna M. Schafer (ORCID: https://orcid.org/0000-0001-7834-5621)
- Emily G Fitts
- Ryan A Elaoud
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- The Ohio State University Wexner Medical Center (US)
- Convergent Science (United States) (US)
- Veterinary Diagnostics Institute (US)
- University of Houston (US)
- The Ohio State University (US)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/jitc-2025-012050
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- Ohio State University
- Pelotonia
- National Institutes of Health
- National Cancer Institute