Figure 4 from Late-Stage Outcomes as Surrogates for Mortality in Cancer Screening Trials: A Systematic Review and Meta-analysis

<p>Exploratory analysis of the effect of the timing of the reporting of late-stage incidence on the association with the mortality outcome. The figure includes trials that reported their late-stage outcomes at least twice [at intervention phase (triangles), earlier than mortality (circles), and/or at mortality (squares)]. Each trial is then represented by two or up to three points connected by a straight line drawn at the main estimate of the screening effect on cancer-specific mortality; this line shows how the estimates of the screening effect on the late-stage incidence within a specific trial changed over time. Size of the points corresponds to precision of the mortality result (inverse variance of the estimate). Colors denote types of cancer (please see the legend).</p>

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Publication Details

Published
2025-10-03
DOI
https://doi.org/10.1158/1055-9965.30271535
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
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article

Figure 4 from Late-Stage Outcomes as Surrogates for Mortality in Cancer Screening Trials: A Systematic Review and Meta-analysis

Robert Allen Smith, Julia Geppert, Peter David Sasieni, Chris Stinton et al.
Health Systems, Economic Evaluations, Quality of Life
article

Figure 4 from Late-Stage Outcomes as Surrogates for Mortality in Cancer Screening Trials: A Systematic Review and Meta-analysis

Robert Allen Smith, Julia Geppert, Peter David Sasieni, Chris Stinton, Matejka Rebolj, Stephen William Duffy, Bethany Shinkins, Ruth Etzioni, Sam M. Janes, Samantha Johnson, Matthew J. Randell, Sian Taylor‐Phillips, Adam R. Brentnall, Karoline Freeman, Nefeli Kouppa
article en

Abstract

<p>Exploratory analysis of the effect of the timing of the reporting of late-stage incidence on the association with the mortality outcome. The figure includes trials that reported their late-stage outcomes at least twice [at intervention phase (triangles), earlier than mortality (circles), and/or at mortality (squares)]. Each trial is then represented by two or up to three points connected by a straight line drawn at the main estimate of the screening effect on cancer-specific mortality; this line shows how the estimates of the screening effect on the late-stage incidence within a specific trial changed over time. Size of the points corresponds to precision of the mortality result (inverse variance of the estimate). Colors denote types of cancer (please see the legend).</p>

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