Immune checkpoint inhibitor therapy and risk of type 1 diabetes mellitus in metastatic cancer patients
ICIs significantly increase the risk of T1DM and DKA. These findings highlight the need for vigilant glycemic monitoring in cancer patients treated with ICIs, especially within identified high-risk subgroups.
Authors
- Ming‐Hsun Lin (ORCID: https://orcid.org/0000-0003-4169-921X)
- Hsin‐Yu Chen (ORCID: https://orcid.org/0000-0002-2765-1685)
- Ching‐Liang Ho (ORCID: https://orcid.org/0000-0002-8378-1687)
- Cho‐Hao Lee (ORCID: https://orcid.org/0000-0002-6061-5168)
- Li‐Ting Kao (ORCID: https://orcid.org/0000-0003-0692-7408)
- Ren-Hua Ye
- Hong‐Jie Jhou (ORCID: https://orcid.org/0000-0003-3304-4643)
- Tina Yi Jin Hsieh (ORCID: https://orcid.org/0000-0001-6296-0689)
- Pau‐Chung Chen (ORCID: https://orcid.org/0000-0002-6242-5974)
- Xiaoyi Zhang (ORCID: https://orcid.org/0000-0001-5124-4919)
- Yuhan Chen (ORCID: https://orcid.org/0000-0002-2950-2675)
- Ming‐Shen Dai (ORCID: https://orcid.org/0000-0002-3953-5243)
- Andrea Yue-En Sun
Institutions
- Tri-Service General Hospital (TW)
- Albert Einstein College of Medicine (US)
- Beth Israel Deaconess Medical Center (US)
- National Yang Ming Chiao Tung University (TW)
- Englewood Hospital and Medical Center (US)
- Jacobi Medical Center (US)
- Taipei Tzu Chi Hospital (TW)
- Chi Mei Medical Center (TW)
- Changhua Christian Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s13098-025-01940-0
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tri-Service General Hospital