Exploring causal relationships between epigenetic age acceleration and Alzheimer’s disease: a bidirectional Mendelian randomization study
Our MR study indicates a positive causal relationship between EAA and AD. Further research is necessary to explore the underlying physiological mechanisms.
Authors
- Hongwei Liu (ORCID: https://orcid.org/0000-0003-2501-7813)
- Zhijun Wang (ORCID: https://orcid.org/0000-0002-9221-2224)
- Xuan Chen (ORCID: https://orcid.org/0000-0001-5553-3638)
- Z X Yin (ORCID: https://orcid.org/0009-0006-3342-4311)
Institutions
- Taiyuan Central Hospital (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s13148-025-01976-z
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00