Seminal plasma cfDNA fragmentomics landscape delineates male infertility subtypes
The study indicates that distinct cfDNA profiles are present in certain male infertility conditions. These cfDNA metrics demonstrated disease-specific cfDNA dynamics present innovative opportunities for the development of noninvasive diagnostic tools in the field of reproductive medicine.
Authors
- Meng Fan (ORCID: https://orcid.org/0000-0002-3761-4431)
- Kai Zhao (ORCID: https://orcid.org/0000-0001-6680-3672)
- Xiaoyu Wu (ORCID: https://orcid.org/0000-0003-3979-1770)
- Zeqing Li (ORCID: https://orcid.org/0000-0002-5131-6625)
- Huiping Zhang (ORCID: https://orcid.org/0000-0002-4902-0104)
Institutions
- Hubei University of Science and Technology (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s13148-025-01973-2
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Science Foundation
- National Key Research and Development Program of China