EVALUATION OF DRUG USE IN HEPATITIS AND ASSOCIATED ADVERSE DRUG REACTIONS IN PEDIATRIC PATIENTS: A PROSPECTIVE OBSERVATIONAL STUDY.

Background:-Diabetes mellitus an emerging global epidemic, is a multifactorial syndrome having a strong genetic connection.ABO blood group antigen which is a genetically determined variable also plays a important role in understanding inheritance pattern and disease susceptibility.The previous studies reported that there are various associations between particular ABO phenotypes and an increased susceptibility to disease. The rationale behind this study was that there might be an association between the ABO blood group and diabetes mellitus and based on result we can identify the susceptible and adopt some preventive measures to decrease the burden of disease in society. Materials and method:-499 individuals were recruited in the study.Out of which 249 were diabetic individual and 250 were control. Result;-Using blood group O as reference the odds ratio was calculated to see the association of different ABO blood group with diabetes mellitus .It was found that Blood group B showed a five times increase risk for development of diabetes mellitus. Conclusion:-The present study shows a significant relationship between blood group B and type 2 diabetes mellitus