Andexanet alfa–induced heparin resistance during percutaneous coronary intervention for ST-elevation myocardial infarction: a case report

Although STEMI following andexanet alfa administration has been reported, this case underscores the additional challenge of profound heparin resistance compromising timely anticoagulation during emergent PCI. Rapid recognition of andexanet alfa-induced heparin resistance is crucial in urgent PCI settings to ensure effective anticoagulation and prevent procedural delays that may compromise outcomes.