Red‐light flashing pens and seizures in children

Photosensitive epilepsy is the most common form of stimulus-induced epilepsy. We describe two unrelated females aged 9 years and 10 years, with prolonged photic-induced absence seizures triggered by a commercially available red-light flashing pen popular among children. Both patients underwent clinical assessment and electroencephalography (EEG) with intermittent photic stimulation. Their EEGs showed a generalized photoparoxysmal response to intermittent photic stimulation. Exposure to the pen, performed in the 9-year-old, elicited a powerful photoparoxysmal discharge. Both patients were successfully treated with valproic acid, preventative measures, and avoidance of known triggers. These observations highlight the risk posed by poorly regulated flashing lights in consumer products. Despite past efforts to regulate visual stimuli in video games and media, current regulatory frameworks do not adequately address emerging light-emitting diode-based technologies, leaving vulnerable populations exposed to preventable risks. There is a pressing need for updated safety standards to prevent seizure-provoking stimuli, especially in products marketed to children.

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Publication Details

Journal
Developmental Medicine & Child Neurology
Published
2025-10-03
DOI
https://doi.org/10.1111/dmcn.70001
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
0.00
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article

Red‐light flashing pens and seizures in children

Renzo Guerrini, Simone Gasparini, Simona Balestrini, Francesca Piras et al.
Developmental Medicine & Child Neurology
EEG and Brain-Computer Interfaces
article

Red‐light flashing pens and seizures in children

Renzo Guerrini, Simone Gasparini, Simona Balestrini, Francesca Piras, Alice Dainelli
article en

Abstract

Photosensitive epilepsy is the most common form of stimulus-induced epilepsy. We describe two unrelated females aged 9 years and 10 years, with prolonged photic-induced absence seizures triggered by a commercially available red-light flashing pen popular among children. Both patients underwent clinical assessment and electroencephalography (EEG) with intermittent photic stimulation. Their EEGs showed a generalized photoparoxysmal response to intermittent photic stimulation. Exposure to the pen, performed in the 9-year-old, elicited a powerful photoparoxysmal discharge. Both patients were successfully treated with valproic acid, preventative measures, and avoidance of known triggers. These observations highlight the risk posed by poorly regulated flashing lights in consumer products. Despite past efforts to regulate visual stimuli in video games and media, current regulatory frameworks do not adequately address emerging light-emitting diode-based technologies, leaving vulnerable populations exposed to preventable risks. There is a pressing need for updated safety standards to prevent seizure-provoking stimuli, especially in products marketed to children.

Developmental Medicine & Child Neurology
Meyer Children's Hospital (IT), University of Florence (IT)
Openalex Percentile: Top 73%
EEG and Brain-Computer Interfaces
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