Quantifying Morbidity Risk Attributed to Red‐Cell Transfusion Volume in Optimally Transfused Patients With β‐Thalassemia
In the long-term follow up study (de-LIGHT), the magnitude of transfusion burden was significantly and incrementally associated with morbidity development in transfusion-dependent patients achieving target hemoglobin thresholds.
Authors
- Emanuela Fecarotta
- Aurelio Maggio (ORCID: https://orcid.org/0000-0002-9601-900X)
- Martina Culcasi (ORCID: https://orcid.org/0009-0000-2718-2404)
- Theodora Maria Venou
- Alessandro Inzerillo
- Antonio Troia
- Paolo Ricchi (ORCID: https://orcid.org/0000-0001-7361-3308)
- Khaled M. Musallam (ORCID: https://orcid.org/0000-0003-3935-903X)
- Angela Vitrano (ORCID: https://orcid.org/0000-0002-1037-1767)
- Maria Concetta Renda (ORCID: https://orcid.org/0000-0003-0260-0256)
- Filomena Longo (ORCID: https://orcid.org/0000-0002-0434-0382)
- Rita Maria Elisa Barone (ORCID: https://orcid.org/0000-0001-6302-2686)
- Antonino Giambona (ORCID: https://orcid.org/0000-0002-5147-9547)
- Giovan Battista Ruffo (ORCID: https://orcid.org/0000-0003-0997-893X)
- Rosario Di Maggio (ORCID: https://orcid.org/0000-0001-9568-9688)
- Efthymia Vlachaki (ORCID: https://orcid.org/0000-0002-2043-9630)
- Brunella Ziello
- Elena Colizzi
- Antonino Giangreco
- Marilena Serra
Institutions
- Cornell University (US)
- Aristotle University of Thessaloniki (GR)
- Ospedale Vincenzo Cervello (IT)
- Fatebenefratelli Hospital (IT)
- Regione Siciliana (IT)
- Ippokrateio General Hospital of Thessaloniki (GR)
- Center for Cancers and Blood Disorders (US)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Ospedale Vito Fazzi (IT)
- St. Anna Hospital (DE)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- American Journal of Hematology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1002/ajh.70100
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agios Pharmaceuticals