Predictors of damage accrual in childhood-onset SLE: a retrospective analysis from a tertiary lupus centre in Türkiye
Our study confirms that higher median disease activity over time, haemolytic anaemia and renal disease are significant predictors of long-term damage in cSLE. Additionally, growth failure was the most frequently involved domain in PedSDI, followed by renal and neuropsychiatric domains. These findings underscore the importance of early and effective disease management and regular monitoring for these risk factors.
Authors
- Nergis Akay (ORCID: https://orcid.org/0000-0001-6102-4055)
- Mehmet Yıldız (ORCID: https://orcid.org/0000-0002-7834-4909)
- Aybüke Gunalp (ORCID: https://orcid.org/0000-0003-0137-0460)
- Amra Adrovic (ORCID: https://orcid.org/0000-0002-2400-6955)
- Fatih Haşlak (ORCID: https://orcid.org/0000-0002-6963-9668)
- Kaan Can Demirbaş (ORCID: https://orcid.org/0000-0003-0620-8155)
- Esma Aslan (ORCID: https://orcid.org/0000-0002-7554-3320)
- Kenan Barut (ORCID: https://orcid.org/0000-0001-8459-2872)
- Oya Köker (ORCID: https://orcid.org/0000-0002-0101-9585)
- Emel Aslan (ORCID: https://orcid.org/0009-0002-4097-7564)
- Özgür Kasapçopur (ORCID: https://orcid.org/0000-0002-1125-7720)
- Sezgin Şahin (ORCID: https://orcid.org/0000-0002-5365-3457)
- Ümit Gül (ORCID: https://orcid.org/0000-0002-1282-8273)
- Alperen Eravsar
Institutions
- Istanbul University-Cerrahpaşa (TR)
- Istanbul University (TR)
Publication Details
- Journal
- Lupus Science & Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/lupus-2025-001634
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00