Design and simulation-based optimization of an ion optical focusing structure for a chip-scale time-of-flight mass spectrometer

To address the challenges of ion divergence and low transmission efficiency during ion transport in miniature time-of-flight mass spectrometers (TOF-MS), which severely degrade sensitivity and other performance metrics, an ion optical focusing structure was designed. Through simulation and computational analysis, optimal electrical parameters were determined to effectively reduce ion divergence angles and enhance transmission efficiency. Experimental verification demonstrated that the ion transmission efficiency increased by over 35% when utilizing electrostatic lens focusing. This study provides valuable insights and practical guidance for the design of ion transmission structures and the optimization of electrical parameters in micro mass spectrometers.

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Publication Details

Published
2025-10-03
DOI
https://doi.org/10.1117/12.3087821
Primary Topic
Ion-surface interactions and analysis
Type
article
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article

Design and simulation-based optimization of an ion optical focusing structure for a chip-scale time-of-flight mass spectrometer

Dou Renchao, Zhigang Zhao, Xinfa Yu, Cui Yuhao
Ion-surface interactions and analysis
article

Design and simulation-based optimization of an ion optical focusing structure for a chip-scale time-of-flight mass spectrometer

Dou Renchao, Zhigang Zhao, Xinfa Yu, Cui Yuhao
article en

Abstract

To address the challenges of ion divergence and low transmission efficiency during ion transport in miniature time-of-flight mass spectrometers (TOF-MS), which severely degrade sensitivity and other performance metrics, an ion optical focusing structure was designed. Through simulation and computational analysis, optimal electrical parameters were determined to effectively reduce ion divergence angles and enhance transmission efficiency. Experimental verification demonstrated that the ion transmission efficiency increased by over 35% when utilizing electrostatic lens focusing. This study provides valuable insights and practical guidance for the design of ion transmission structures and the optimization of electrical parameters in micro mass spectrometers.

China Academy of Space Technology (CN)
Openalex Percentile: Top 71%
Ion-surface interactions and analysis
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