Intra-arterial bleomycin for treatment of labial arteriovenous malformations in children

Labial arteriovenous malformations (AVMs) pose a great challenge due to their location, angiogenic potential, and recurrence rate. Emerging treatments include sclerotherapy, such as intra-arterial bleomycin, which has been proven safe and effective in adults; however, there is limited literature available for children. Here, we present two successful cases of intra-arterial bleomycin use for treating lip AVMs in children, resulting in complete cure and no recurrence after a two-year follow-up period. Our findings support the limited but growing body of literature that presents intra-arterial bleomycin as a safe and viable option for pediatric facial AVMs.

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Publication Details

Journal
Interventional Neuroradiology
Published
2025-10-03
DOI
https://doi.org/10.1177/15910199251380362
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
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article

Intra-arterial bleomycin for treatment of labial arteriovenous malformations in children

Mirindi Kabangu, Luis Octavio Tierradentro‐García, Juan Tejada
Interventional Neuroradiology
Vascular Malformations and Hemangiomas
article

Intra-arterial bleomycin for treatment of labial arteriovenous malformations in children

Mirindi Kabangu, Luis Octavio Tierradentro‐García, Juan Tejada
article en

Abstract

Labial arteriovenous malformations (AVMs) pose a great challenge due to their location, angiogenic potential, and recurrence rate. Emerging treatments include sclerotherapy, such as intra-arterial bleomycin, which has been proven safe and effective in adults; however, there is limited literature available for children. Here, we present two successful cases of intra-arterial bleomycin use for treating lip AVMs in children, resulting in complete cure and no recurrence after a two-year follow-up period. Our findings support the limited but growing body of literature that presents intra-arterial bleomycin as a safe and viable option for pediatric facial AVMs.

Interventional Neuroradiology
Children's Hospital of Philadelphia (US), Riley Hospital for Children (US), Seattle Children's Hospital (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 56%
Vascular Malformations and Hemangiomas
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Intra-arterial bleomycin for treatment of labial arteriovenous malformations in children — Mirindi Kabangu, Luis Octavio Tierradentro‐García, et al. · Interventional Neuroradiology (2025) | TGRS Research Map | TGRS