Intra-arterial bleomycin for treatment of labial arteriovenous malformations in children
Labial arteriovenous malformations (AVMs) pose a great challenge due to their location, angiogenic potential, and recurrence rate. Emerging treatments include sclerotherapy, such as intra-arterial bleomycin, which has been proven safe and effective in adults; however, there is limited literature available for children. Here, we present two successful cases of intra-arterial bleomycin use for treating lip AVMs in children, resulting in complete cure and no recurrence after a two-year follow-up period. Our findings support the limited but growing body of literature that presents intra-arterial bleomycin as a safe and viable option for pediatric facial AVMs.
Authors
- Mirindi Kabangu (ORCID: https://orcid.org/0000-0002-4605-9089)
- Luis Octavio Tierradentro‐García (ORCID: https://orcid.org/0000-0003-1164-4656)
- Juan Tejada (ORCID: https://orcid.org/0000-0002-1374-1903)
Institutions
- Children's Hospital of Philadelphia (US)
- Riley Hospital for Children (US)
- Seattle Children's Hospital (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Interventional Neuroradiology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1177/15910199251380362
- Primary Topic
- Vascular Malformations and Hemangiomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00