Deferoxamine attenuates sepsis-induced liver injury by suppressing ferroptosis
Ferroptosis plays a critical role in the pathogenesis of sepsis-induced liver injury. Targeting the activation of ferroptosis in hepatocytes during sepsis through intervention with DFO may represent a promising therapeutic strategy for the management of this condition.
Authors
- Hongyao Li (ORCID: https://orcid.org/0009-0007-8195-0452)
- Shixian Liu (ORCID: https://orcid.org/0000-0001-9629-096X)
- Jiahui Zheng (ORCID: https://orcid.org/0000-0003-3758-9149)
- Peiwu Li (ORCID: https://orcid.org/0000-0003-2671-7811)
- Haidan Zhang
Institutions
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Immunobiology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1016/j.imbio.2025.153125
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00