Statins, cholesterol and cognition at the time of Alzheimer's disease diagnosis: A cross-sectional study from the Swedish registry for cognitive/dementia disorders
Younger AD patients and those with cardiovascular disease were more likely to use statins. Simvastatin use was linked to higher cognitive scores at diagnosis. In non-users, higher LDL-C, TC, and HDL-C levels correlated with better baseline cognitive scores. Longitudinal studies are needed to investigate the effects of statins on cognitive decline in AD.
Authors
- Minh Tuan Hoang (ORCID: https://orcid.org/0000-0002-6776-6655)
- Maria Eriksdotter (ORCID: https://orcid.org/0000-0003-2498-4000)
- Sara García‐Ptacek (ORCID: https://orcid.org/0000-0002-1537-6129)
- Hong Xu (ORCID: https://orcid.org/0000-0002-7266-3431)
- Bojana Petek (ORCID: https://orcid.org/0000-0002-5498-8320)
- Julianna Kele (ORCID: https://orcid.org/0000-0003-3418-1412)
- Minjia Mo (ORCID: https://orcid.org/0000-0002-1932-8423)
- Juan Jesús Carrero (ORCID: https://orcid.org/0000-0003-4763-2024)
- Marta Villa‐Lopez
- Jakob Norgren (ORCID: https://orcid.org/0000-0003-1352-9256)
- Henrike Häbel (ORCID: https://orcid.org/0000-0001-5564-4258)
- Luana Naia (ORCID: https://orcid.org/0000-0002-0886-4634)
- Bengt Winblad (ORCID: https://orcid.org/0000-0002-0011-1179)
- Milica Gregorič Kramberger (ORCID: https://orcid.org/0000-0001-8231-1176)
- Silvia Maioli (ORCID: https://orcid.org/0000-0002-9577-0803)
- Joana B. Pereira (ORCID: https://orcid.org/0000-0002-4604-2711)
Institutions
- Universidad Complutense de Madrid (ES)
- Karolinska University Hospital (SE)
- University of Ljubljana (SI)
- Alberta Hospital Edmonton (CA)
- Ljubljana University Medical Centre (SI)
- University of Alberta Hospital (CA)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Journal of Alzheimer s Disease Reports
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/25424823251385903
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 2.01