Comparison of diagnostic algorithms used in guidelines on nutritional anaemias in adults
There was a lot of variation in the included diagnostic algorithms, especially for iron deficiency anaemia. Differences in cut-off values were seen, even when using similar diagnostic strategies. Furthermore, supporting evidence was variable. Further research is needed to determine optimal algorithms. Our findings highlight the need for inclusion of relevant laboratory aspects in guidelines, appropriate diagnostics and clinical decision limits.
Authors
- Steef Kurstjens (ORCID: https://orcid.org/0009-0008-4409-5079)
- Anne Margreet de Jong (ORCID: https://orcid.org/0000-0002-9638-9115)
- Jacobijn Gussekloo (ORCID: https://orcid.org/0000-0001-7186-8278)
- Wendy P. J. den Elzen (ORCID: https://orcid.org/0000-0002-6774-4077)
- Rosalinde K.E. Poortvliet
- B. Boer
- Margaretha G. M. Roemer
Institutions
- Leiden University Medical Center (NL)
- Noordwest Ziekenhuisgroep (NL)
- Amsterdam Neuroscience (NL)
- Canisius-Wilhelmina Ziekenhuis (NL)
- Centre for Human Drug Research (NL)
- Public Health Service of Amsterdam (NL)
- Amsterdam University Medical Centers (NL)
- Jeroen Bosch Ziekenhuis (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1371/journal.pone.0333688
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00