Association of serum intestinal fatty-acid binding protein, inflammatory and oxidative stress markers with colorectal cancer among Ghanaian patients
The study identifies TNF-α and MDA as potential biomarkers associated with CRC, emphasizing the role of inflammation and oxidative stress in CRC pathogenesis in Ghana. The lack of adjusted association with iFABP may reflect population-specific patterns or limited statistical power. Further large-scale longitudinal studies are warranted.
Authors
- Antoinette Bediako‐Bowan (ORCID: https://orcid.org/0000-0002-9725-1839)
- Genevieve Kwao‐Zigah (ORCID: https://orcid.org/0009-0006-1691-5418)
- Emmanuel Ayitey Tagoe (ORCID: https://orcid.org/0000-0001-7179-1872)
- Osbourne Quaye (ORCID: https://orcid.org/0000-0002-0621-876X)
- Gloria Kezia Aryee
- Gabriel Atampugbire (ORCID: https://orcid.org/0009-0001-2864-8453)
- Caleb Koranteng Kwayisi‐Darkwah
Institutions
- University of Ghana (GH)
- University of Health and Allied Sciences (GH)
- Korle Bu Teaching Hospital (GH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1371/journal.pone.0333799
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Ghana