Injection of Fluorescent Neural Progenitor Cells into Human Cerebral Organoids for Transplantation Modeling

Source: Ibanez-Rios, M.I., et al., A Human Cerebral Organoid Model of Neural Cell Transplantation. J. Vis. Exp. (2023)This video demonstrates the injection of fluorescently labeled neural progenitor cells (NPCs) into human cerebral organoids using a cell-matrix mixture. The method is reproducible and animal-free, enabling transplantation with minimal organoid disruption. It offers a valuable platform for modeling neural transplants and central nervous system (CNS) diseases.