Acute Surgery vs Conservative Treatment for Traumatic Acute Subdural Hematoma
In this comparative effectiveness study, similar patients with traumatic ASDH were treated differently due to center-specific treatment preferences. Outcomes were similar in centers preferring surgical evacuation and those preferring initial conservative treatment. This study suggests that, for a patient with ASDH for whom a neurosurgeon experiences clinical equipoise between acute surgery vs (initial) conservative treatment, conservative treatment may be considered.
Authors
- Jason Barber (ORCID: https://orcid.org/0000-0002-3016-7800)
- Thomas A. van Essen (ORCID: https://orcid.org/0000-0003-4657-5283)
- Frederick K. Korley (ORCID: https://orcid.org/0000-0003-4920-8278)
- Leila L. Etemad (ORCID: https://orcid.org/0000-0002-7047-6587)
- David M. Schnyer (ORCID: https://orcid.org/0000-0002-7472-2853)
- Laura B. Ngwenya (ORCID: https://orcid.org/0000-0001-7103-971X)
- Ross Zafonte (ORCID: https://orcid.org/0000-0002-1050-796X)
- Michael McCrea (ORCID: https://orcid.org/0000-0001-9791-9475)
- Wouter A. Moojen (ORCID: https://orcid.org/0000-0001-6332-5505)
- Gabriela Satris
- Amy J. Markowitz (ORCID: https://orcid.org/0000-0001-9314-2814)
- Godard C. W. de Ruiter (ORCID: https://orcid.org/0000-0003-0764-8048)
- Dana Pisică
- Hester F. Lingsma (ORCID: https://orcid.org/0000-0003-2063-9533)
- Vincent Y. Wang
- Nancy Temkin (ORCID: https://orcid.org/0000-0002-6392-5292)
- Jeroen TJM van Dijck
- Ramon Diaz‐Arrastia (ORCID: https://orcid.org/0000-0001-6051-3594)
- Mary J. Vassar (ORCID: https://orcid.org/0000-0001-6748-6939)
- Wilco C. Peul
- Sonia Jain (ORCID: https://orcid.org/0000-0001-8408-1247)
- Ramesh Grandhi (ORCID: https://orcid.org/0000-0001-9000-6083)
- Vijay Krishnamoorthy (ORCID: https://orcid.org/0000-0003-4153-2348)
- Brian Fabian
- Pratik Mukherjee (ORCID: https://orcid.org/0000-0001-7473-7409)
- Esther L. Yuh (ORCID: https://orcid.org/0000-0002-1180-2274)
- Yelena G. Bodien (ORCID: https://orcid.org/0000-0003-4858-2903)
- Joseph T. Giacino (ORCID: https://orcid.org/0000-0002-7916-9698)
- Claudia S. Robertson
- Ava M. Puccio (ORCID: https://orcid.org/0000-0003-2569-9607)
- Mahmoud Elguindy (ORCID: https://orcid.org/0000-0001-9151-1751)
- Peter J. Hutchinson (ORCID: https://orcid.org/0000-0002-2796-1835)
- Alex B. Valadka (ORCID: https://orcid.org/0000-0003-0156-1531)
- Brandon Foreman (ORCID: https://orcid.org/0000-0002-5418-674X)
- Sabrina R. Taylor (ORCID: https://orcid.org/0000-0003-4867-1922)
- Hugo F. den Boogert
- Geoffrey A. Manley (ORCID: https://orcid.org/0000-0002-4950-4651)
- John K. Yue (ORCID: https://orcid.org/0000-0001-9694-7722)
- Christine J. Gotthardt (ORCID: https://orcid.org/0009-0002-9251-2005)
- Ewout W. Steyerberg (ORCID: https://orcid.org/0000-0002-7787-0122)
- Andrew I.R. Maas (ORCID: https://orcid.org/0000-0003-1612-1264)
- Christine Mac Donald
- Randall E. Merchant
- David O. Okonkwo
- Xiaoying Sun
- Shawn R. Eagly
Institutions
- San Francisco General Hospital (US)
- Harvard University (US)
- University of Antwerp (BE)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- Medical College of Wisconsin (US)
- University of Cambridge (GB)
- Spaulding Rehabilitation Hospital (US)
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- Medisch Centrum Haaglanden (NL)
- Antwerp University Hospital (BE)
- Knowledge Foundation (SE)
- Addenbrooke's Hospital (GB)
- Neurological Surgery (US)
- University of Cincinnati (US)
- University of Pennsylvania (US)
- The University of Texas at Austin (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.35200
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- U.S. Department of Defense
- Abbott Laboratories
- Neurosurgery Research and Education Foundation
- Integra LifeSciences
- One Mind
- European Commission
- ZonMw
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- ZNS - Hannelore Kohl Stiftung
- Hersenstichting
- University of California, San Francisco