A retrospective study on clozapine-induced blood dyscrasias in the first 20 weeks of therapy

CZP treatment resulted in more blood disorders than TA or AA treatments. While blood abnormalities were common with CZP, severe neutropenia was rare. Certain blood changes were linked to better treatment outcomes. Therefore, regular blood monitoring is recommended to optimize treatment effectiveness and manage side effects.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2025-10-03
DOI
https://doi.org/10.1016/j.jpsychires.2025.09.081
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

A retrospective study on clozapine-induced blood dyscrasias in the first 20 weeks of therapy

Ali Ahsan Mufti, Dieter Deforce, Yannick Gansemans, Filip Van Nieuwerburgh et al.
Journal of Psychiatric Research
Schizophrenia research and treatment
article

A retrospective study on clozapine-induced blood dyscrasias in the first 20 weeks of therapy

Ali Ahsan Mufti, Dieter Deforce, Yannick Gansemans, Filip Van Nieuwerburgh, Mohsin Ali, Abdur Razaq, H Ali
article en

Abstract

CZP treatment resulted in more blood disorders than TA or AA treatments. While blood abnormalities were common with CZP, severe neutropenia was rare. Certain blood changes were linked to better treatment outcomes. Therefore, regular blood monitoring is recommended to optimize treatment effectiveness and manage side effects.

Journal of Psychiatric ResearchVol. 191
Khyber Medical University (PK), Lady Reading Hospital (PK), Ghent University (BE)
Higher Education Commision, Pakistan
Openalex Percentile: Top 67%
Schizophrenia research and treatment
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