Not all “<i>Candida</i>” are “<i>Candida</i>”: <i>Nakaseomyces glabratus</i> (H.W. Anderson) Sugita &amp; M. Takask. 2022 onychomycosis and the need for rapid diagnostic

Onychomycosis is a common nail disorder typically caused by dermatophytes, with Candida species and non-dermatophytic molds being less frequent agents. Nakaseomyces glabratus (formerly Candida glabrata) is a rare cause of nail infections, notable for its intrinsic resistance to azoles and diagnostic challenges. We report a case of chronic nail discoloration, thickening, and fragility initially misdiagnosed as psoriasis. Microscopy and culture, followed by selective medium analysis, confirmed N. glabratus infection. This case emphasizes the importance of considering uncommon yeast species and highlights both the need for accurate identification to guide therapy and the possible misdiagnosis with other pathologies. Awareness and proper diagnostic approaches are essential for timely and effective management of such rare fungal nail infections.

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Publication Details

Journal
FEMS Microbiology Letters
Published
2025-01-01
DOI
https://doi.org/10.1093/femsle/fnaf107
Citations
1
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
1.35
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article

Not all “Candida” are “Candida”: Nakaseomyces glabratus (H.W. Anderson) Sugita & M. Takask. 2022 onychomycosis and the need for rapid diagnostic

Mirko Benvenuti, Antonino Torino, Emanuele Cozzani, Giulia Gasparini
1 citations
FEMS Microbiology Letters
Nail Diseases and Treatments
1.35
article

Not all “Candida” are “Candida”: Nakaseomyces glabratus (H.W. Anderson) Sugita & M. Takask. 2022 onychomycosis and the need for rapid diagnostic

Mirko Benvenuti, Antonino Torino, Emanuele Cozzani, Giulia Gasparini
article en
1 citations

Abstract

Onychomycosis is a common nail disorder typically caused by dermatophytes, with Candida species and non-dermatophytic molds being less frequent agents. Nakaseomyces glabratus (formerly Candida glabrata) is a rare cause of nail infections, notable for its intrinsic resistance to azoles and diagnostic challenges. We report a case of chronic nail discoloration, thickening, and fragility initially misdiagnosed as psoriasis. Microscopy and culture, followed by selective medium analysis, confirmed N. glabratus infection. This case emphasizes the importance of considering uncommon yeast species and highlights both the need for accurate identification to guide therapy and the possible misdiagnosis with other pathologies. Awareness and proper diagnostic approaches are essential for timely and effective management of such rare fungal nail infections.

FEMS Microbiology LettersVol. 372
Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Openalex Percentile: Top 15%
Nail Diseases and Treatments
1.35
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