Platelet-like cells differentiated from adipose-derived mesenchymal stem cells inhibit acute inflammation of tendinopathy in rats
ASCL-PLC has advantages over existing PRP therapies, including the ability to be cryopreserved after quality checks, and homogeneous populations of ASCL-PLCs can be prepared in large quantity. We conclude that in the future ASCL-PLCs may serve as an allogeneic transplant effective to treat tendinopathy.
Authors
- Masaya Nakamura (ORCID: https://orcid.org/0000-0001-7916-5497)
- Takeshi Miyamoto (ORCID: https://orcid.org/0000-0001-8658-9546)
- Yukako Ono‐Uruga
- Yosuke Kaneko (ORCID: https://orcid.org/0009-0000-5980-5741)
- Takuji Iwamoto (ORCID: https://orcid.org/0000-0002-7605-6727)
- Satoshi Nakamura (ORCID: https://orcid.org/0000-0002-1864-7369)
- Yuichi Yamada
- Kazuki Sato (ORCID: https://orcid.org/0000-0002-0586-1868)
- Morio Matsumoto (ORCID: https://orcid.org/0000-0001-9791-0139)
- Yumiko Matsubara
- Akiko Torii
- Yuiko Sato
Institutions
- Keio University (JP)
- Kumamoto University Hospital (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Journal of Bone and Mineral Metabolism
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1007/s00774-025-01647-2
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00