Transcriptomic and Clinical Profiling Reveals LGALS3 as a Prognostic Oncogene in Pancreatic Cancer

These findings identify Galectin-3 as a key regulator of oncogenic programs and a potential prognostic biomarker in PDAC and other malignancies, with implications for therapeutic targeting.

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Publication Details

Journal
Genes
Published
2025-10-03
DOI
https://doi.org/10.3390/genes16101170
Primary Topic
Galectins and Cancer Biology
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic and Clinical Profiling Reveals LGALS3 as a Prognostic Oncogene in Pancreatic Cancer

Paolo Fagone, Michelino Di Rosa, Gian Marco Leone, Katia Mangano et al.
Genes
Galectins and Cancer Biology
article

Transcriptomic and Clinical Profiling Reveals LGALS3 as a Prognostic Oncogene in Pancreatic Cancer

Paolo Fagone, Michelino Di Rosa, Gian Marco Leone, Katia Mangano, Sanja Mijatović, José Francisco Muñóz-Valle, Danijela Maksimović‐Ivanić, Alexis Missael Vizcaíno‐Quirarte, Ferdinando Nicoletti, Grazia Scuderi
article en

Abstract

These findings identify Galectin-3 as a key regulator of oncogenic programs and a potential prognostic biomarker in PDAC and other malignancies, with implications for therapeutic targeting.

GenesVol. 16(10)
Universidad de Guadalajara (MX), University of Catania (IT), University of Belgrade (RS)
Openalex Percentile: Top 71%
Galectins and Cancer Biology
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Transcriptomic and Clinical Profiling Reveals LGALS3 as a Prognostic Oncogene in Pancreatic Cancer — Paolo Fagone, Michelino Di Rosa, et al. · Genes (2025) | TGRS Research Map | TGRS