Chronic Stress, Calcium Signaling, and Neurotransmitter Dysregulation: A Molecular Disruption of Learning and Memory

This paper will review how chronic stress interferes with calcium homeostasis and synaptic plasticity. Special emphasis will be placed on the molecular pathways of glucocorticoid action, the disruption of calcium signaling, the impairments in long-term potentiation (LTP) and neurotransmitter release, and broader cognitive and psychiatric implications.