Exploratory high-throughput screening of repurposed drugs for canine lymphoid malignancies

This exploratory screening study identified clinically approved drugs with available pharmacokinetic data as candidate therapeutic agents for the treatment of canine lymphoid malignancies. Based on this study, further studies are warranted to validate the in vivo efficacy and elucidate the underlying mechanisms of candidate drugs in canine lymphoid malignancies.

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Publication Details

Journal
BMC Veterinary Research
Published
2025-10-03
DOI
https://doi.org/10.1186/s12917-025-05053-8
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploratory high-throughput screening of repurposed drugs for canine lymphoid malignancies

Atsushi Tsukamoto, Masaki Ishida, Hirotaka Tomiyasu, M. Nishida et al.
BMC Veterinary Research
Virus-based gene therapy research
article

Exploratory high-throughput screening of repurposed drugs for canine lymphoid malignancies

Atsushi Tsukamoto, Masaki Ishida, Hirotaka Tomiyasu, M. Nishida, Hiroki Sakuma, Shinichiro Nakamura, Emia Daiku, Mari Takamiya
article en

Abstract

This exploratory screening study identified clinically approved drugs with available pharmacokinetic data as candidate therapeutic agents for the treatment of canine lymphoid malignancies. Based on this study, further studies are warranted to validate the in vivo efficacy and elucidate the underlying mechanisms of candidate drugs in canine lymphoid malignancies.

BMC Veterinary ResearchVol. 21(1)
Azabu University (JP), The University of Tokyo (JP)
Japan Agency for Medical Research and Development, Veterinärmedizinische Universität Wien, Japan Society for the Promotion of Science
Openalex Percentile: Top 71%
Virus-based gene therapy research
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