Probiotic Bacillus subtilis enhances silkworm (Bombyx mori) growth performance and silk production via modulating gut microbiota and amino acid metabolism
B. subtilis enhances silkworm growth and silk production through multi-faceted mechanisms: reshaping gut microbiota composition, improving digestive enzyme activity, and elevating phenylalanine biosynthesis. These findings establish B. subtilis as a promising probiotic for optimizing artificial diet systems in Lepidoptera and highlight the central role of amino acid metabolism in insect-microbiome symbiosis.
Authors
- Chunjiu Ren (ORCID: https://orcid.org/0000-0001-5919-8144)
- Changjun Liu (ORCID: https://orcid.org/0000-0003-4146-9510)
- Xin Fan (ORCID: https://orcid.org/0000-0003-4745-0837)
- Yingchen Meng
- Shengxiang Zhang (ORCID: https://orcid.org/0000-0001-6524-9673)
- Yangyang Liu (ORCID: https://orcid.org/0000-0001-8547-0172)
- Yating Liu
- Yi Wang (ORCID: https://orcid.org/0000-0003-4133-9273)
- Huizhen Wang
Institutions
- Yibin University (CN)
- State Forestry and Grassland Administration (CN)
- Shandong Agricultural University (CN)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s42523-025-00473-1
- Primary Topic
- Insect symbiosis and bacterial influences
- Type
- article
- Field-Weighted Citation Impact
- 0.00