Are Rhinitis and Asthma Just One Disease Affecting Different Parts of the Respiratory Tract?

Both allergic rhinitis and chronic rhinosinusitis with or without nasal polyps have important factors in common with asthma. They are often present simultaneously, they have similar pathogenesis processes, and they have synergistic effects on the clinical manifestations. There are also important considerations regarding the common treatment of these pathologies. Taking all these into account, it is possible to place these diseases under the “united airway disease” umbrella. However, matters such as embryologic origins, anatomy and function of the upper and lower airways, as well as cases where the aforementioned pathologies can be observed independently and have different treatment responses, make up reasonable counterarguments for the “united airway disease”. This narrative review attempts to put all these factors into perspective for a slightly better understanding of the complexity of this topic. We will take into consideration factors such as epidemiological data, pathogenesis and pathology, clinical considerations, and the benefits of a common treatment.

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Publication Details

Journal
Allergies
Published
2025-10-03
DOI
https://doi.org/10.3390/allergies5040034
Citations
1
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
1.16
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article

Are Rhinitis and Asthma Just One Disease Affecting Different Parts of the Respiratory Tract?

Felicia Manole, Alexia Manole, Victor Alexandru
1 citations
Allergies
Asthma and respiratory diseases
1.16
article

Are Rhinitis and Asthma Just One Disease Affecting Different Parts of the Respiratory Tract?

Felicia Manole, Alexia Manole, Victor Alexandru
article en
1 citations

Abstract

Both allergic rhinitis and chronic rhinosinusitis with or without nasal polyps have important factors in common with asthma. They are often present simultaneously, they have similar pathogenesis processes, and they have synergistic effects on the clinical manifestations. There are also important considerations regarding the common treatment of these pathologies. Taking all these into account, it is possible to place these diseases under the “united airway disease” umbrella. However, matters such as embryologic origins, anatomy and function of the upper and lower airways, as well as cases where the aforementioned pathologies can be observed independently and have different treatment responses, make up reasonable counterarguments for the “united airway disease”. This narrative review attempts to put all these factors into perspective for a slightly better understanding of the complexity of this topic. We will take into consideration factors such as epidemiological data, pathogenesis and pathology, clinical considerations, and the benefits of a common treatment.

AllergiesVol. 5(4)
University of Oradea (RO), Spitalul Clinic Dr. Victor Babes (RO)
Openalex Percentile: Top 17%
Asthma and respiratory diseases
1.16
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