Strict retroelement regulation is frequently lost following cancer transformation and generates a promising reservoir of cancer biomarkers
Our data demonstrate that elevated transcription of certain tissue-specific and embryonic retroelements can be considered as a hallmark of tumorigenesis.
Authors
- Eric Russ (ORCID: https://orcid.org/0000-0002-7753-5711)
- Sergey Iordanskiy (ORCID: https://orcid.org/0000-0002-9279-8755)
Institutions
- Henry M. Jackson Foundation (US)
- Uniformed Services University of the Health Sciences (US)
- Palo Alto University (US)
- Stanford University (US)
Publication Details
- Journal
- Mobile DNA
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s13100-025-00376-7
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Uniformed Services University of the Health Sciences