Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field

Recent work highlights nuanced pathways through which early life adversity contributes to the development of a biological foundation underlying risk for non-communicable conditions. We contend that it is crucial to reflect on future research directions to ensure continued progress and opportunities for clinical translation, as the development of an increasingly sophisticated understanding of the pathways linking adversity to illness holds enormous promise for our ability to promote health and prevent disease among at-risk youth.

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Publication Details

Journal
BMC Medicine
Published
2025-10-03
DOI
https://doi.org/10.1186/s12916-025-04388-1
Citations
3
Primary Topic
Birth, Development, and Health
Type
article
Field-Weighted Citation Impact
10.48
Controls
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article

Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field

Ellen Jopling, Charles A. Nelson
3 citations
BMC Medicine
Birth, Development, and Health
10.48
article

Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field

Ellen Jopling, Charles A. Nelson
article en
3 citations

Abstract

Recent work highlights nuanced pathways through which early life adversity contributes to the development of a biological foundation underlying risk for non-communicable conditions. We contend that it is crucial to reflect on future research directions to ensure continued progress and opportunities for clinical translation, as the development of an increasingly sophisticated understanding of the pathways linking adversity to illness holds enormous promise for our ability to promote health and prevent disease among at-risk youth.

BMC MedicineVol. 23(1)
Boston Children's Hospital (US), Harvard University (US)
Openalex Percentile: Top 2%
Birth, Development, and Health
10.48
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