Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field
Recent work highlights nuanced pathways through which early life adversity contributes to the development of a biological foundation underlying risk for non-communicable conditions. We contend that it is crucial to reflect on future research directions to ensure continued progress and opportunities for clinical translation, as the development of an increasingly sophisticated understanding of the pathways linking adversity to illness holds enormous promise for our ability to promote health and prevent disease among at-risk youth.
Authors
- Ellen Jopling (ORCID: https://orcid.org/0000-0001-5518-2364)
- Charles A. Nelson (ORCID: https://orcid.org/0000-0002-4723-247X)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s12916-025-04388-1
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 10.48