Severity of Brachyspira hyodysenteriae colitis correlates to the changes observed in the microbiota composition and its associated functionality in the large intestine
Our study shows that in colitis caused by B. hyo, changes in the microbiota are mainly a consequence of the lesions that occur in the intestine, with no differences observed in early infection. Similarly, the bacterial species that are increased at the onset of clinical signs may promote intestinal inflammation caused by B. hyo infection, but the analysis of their genomes rule out their participation in the primary infection.
Authors
- Juan M. Ortiz Sanjuán (ORCID: https://orcid.org/0000-0001-7697-2277)
- José Francisco Cobo-Díaz (ORCID: https://orcid.org/0000-0002-0898-2358)
- Pedro Rubio (ORCID: https://orcid.org/0000-0002-4267-5650)
- Héctor Puente
- Cristina Galisteo (ORCID: https://orcid.org/0000-0002-6896-2148)
- Héctor Argüello (ORCID: https://orcid.org/0000-0001-8504-2717)
- Lucía Pérez‐Pérez
- Ana Carvajal
Institutions
- Teagasc - The Irish Agriculture and Food Development Authority (IE)
- University of Córdoba (ES)
- Universidad de León (ES)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1186/s42523-025-00466-0
- Primary Topic
- Veterinary medicine and infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00