Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India

<i>Schizophyllum</i> species are emerging human respiratory pathogens. We report India's likely first case of invasive fungal rhinosinusitis by <i>Schizophyllum radiatum.</i> A 32-year-old healthy woman presented with bilateral nasal discharge. Microscopic examination of the sinus aspirate showed septate hyaline hyphae and culture yielded fungal growth with sterile hyphae. The isolate was identified as <i>S. radiatum</i> by sequencing of the ITS region. This highlights the importance of genomic sequencing for the identification of non-sporulating molds.

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Journal
Medical Mycology Case Reports
Published
2025-09-12
DOI
https://doi.org/10.1016/j.mmcr.2025.100732
Primary Topic
Infectious Diseases and Mycology
Type
article
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article

Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India

Priyadarshini A. Padaki, Chithra Valsan, Rosmi Jose, Jayanthi Savio et al.
Medical Mycology Case Reports
Infectious Diseases and Mycology
article

Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India

Priyadarshini A. Padaki, Chithra Valsan, Rosmi Jose, Jayanthi Savio, Ramesh Kumar, Anuja Elizabeth George
article en

Abstract

<i>Schizophyllum</i> species are emerging human respiratory pathogens. We report India's likely first case of invasive fungal rhinosinusitis by <i>Schizophyllum radiatum.</i> A 32-year-old healthy woman presented with bilateral nasal discharge. Microscopic examination of the sinus aspirate showed septate hyaline hyphae and culture yielded fungal growth with sterile hyphae. The isolate was identified as <i>S. radiatum</i> by sequencing of the ITS region. This highlights the importance of genomic sequencing for the identification of non-sporulating molds.

Medical Mycology Case ReportsVol. 50
Jubilee Mission Medical College and Research Institute (IN), St.John's Medical College Hospital (IN)
Openalex Percentile: Top 70%
Infectious Diseases and Mycology
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Schizophyllum radiatum: An uncommon culprit of invasive fungal rhinosinusitis in an immunocompetent patient – A case report from India — Priyadarshini A. Padaki, Chithra Valsan, et al. · Medical Mycology Case Reports (2025) | TGRS Research Map | TGRS