KIAA0319 modulates Alzheimer's disease risk through PMM2 regulation: Evidence from integrated pQTL-mediation and transcriptomic analyses
This integrative analysis uncovered a novel KIAA0319-PMM2 regulatory axis implicated in AD pathogenesis. Both proteins represent potential therapeutic targets for future AD interventions.
Authors
- Chong Han
- Huan Chen (ORCID: https://orcid.org/0000-0002-3498-6088)
- Shanxia Yao
- Hongxin Zhao
- Peng Wen (ORCID: https://orcid.org/0000-0003-1451-497X)
Institutions
- Zunyi Medical University (CN)
- First People’s Hospital of Zunyi (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease Reports
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/25424823251384245
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61