NNMT expression in preeclampsia: Analyses on placental tissues and cell lines
Low NNMT expression found in PE placentas may represent a response to the hypoxia and inflammation featuring this disorder. Therefore, the enzyme could contribute to the normal human placental development, by defending trophoblast cells form PE-induced damages.
Authors
- Sonia Fantone (ORCID: https://orcid.org/0000-0002-5630-5984)
- Giovanni Tossetta (ORCID: https://orcid.org/0000-0001-7003-1230)
- Daniela Marzioni (ORCID: https://orcid.org/0000-0002-2267-0270)
- Monica Emanuelli (ORCID: https://orcid.org/0000-0002-8520-519X)
- Andrea Ciavattini (ORCID: https://orcid.org/0000-0002-8037-4947)
- Stefano Raffaele Giannubilo (ORCID: https://orcid.org/0000-0002-9427-1391)
- Roberto Campagna (ORCID: https://orcid.org/0000-0003-2607-2734)
- Nicoletta Di Simone (ORCID: https://orcid.org/0000-0003-1273-3335)
- Veronica Pompei (ORCID: https://orcid.org/0000-0002-3747-9348)
- Davide Sartini (ORCID: https://orcid.org/0000-0003-3879-8647)
Institutions
- Marche Polytechnic University (IT)
- Humanitas University (IT)
- Ospedali Riuniti di Ancona (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto Nazionale di Riposo e Cura per Anziani (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Placenta
- Published
- 2025-09-26
- DOI
- https://doi.org/10.1016/j.placenta.2025.09.017
- Citations
- 5
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 10.29