[Treatment of pediatric chronic myeloid leukemia].

Treatment strategies for chronic myeloid leukemia (CML) have changed significantly with the development of new tyrosine kinase inhibitors (TKIs). Due to its extreme rarity, pediatric CML has historically been managed based on evidence in adult patients. However, as the unique biological and clinical characteristics of pediatric CML have become increasingly apparent, the need for pediatric-specific treatment guidelines is now widely recognized. This review outlines the treatment of pediatric CML as of 2025, with a focus on clinical trial results from Japan and the latest consensus guidelines issued by the International Pediatric CML Working Group.

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Publication Details

Journal
PubMed
Published
2025-01-01
DOI
https://doi.org/10.11406/rinketsu.66.1241
Primary Topic
Chronic Myeloid Leukemia Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

[Treatment of pediatric chronic myeloid leukemia].

Chikako Tono
PubMed
Chronic Myeloid Leukemia Treatments
article

[Treatment of pediatric chronic myeloid leukemia].

Chikako Tono
article en

Abstract

Treatment strategies for chronic myeloid leukemia (CML) have changed significantly with the development of new tyrosine kinase inhibitors (TKIs). Due to its extreme rarity, pediatric CML has historically been managed based on evidence in adult patients. However, as the unique biological and clinical characteristics of pediatric CML have become increasingly apparent, the need for pediatric-specific treatment guidelines is now widely recognized. This review outlines the treatment of pediatric CML as of 2025, with a focus on clinical trial results from Japan and the latest consensus guidelines issued by the International Pediatric CML Working Group.

PubMedVol. 66(9)
Hirosaki University (JP)
Openalex Percentile: Top 65%
Chronic Myeloid Leukemia Treatments
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