Effects of low-dose growth hormone treatment on obesity: a meta-analysis of randomized controlled trials
Low-dose rhGH therapy significantly reduces visceral fat and enhances thigh muscle mass in obese individuals without GH deficiency. These findings suggest that low-dose rhGH may offer therapeutic potential for sarcopenic obesity, warranting further investigation in larger, longer-term studies.
Authors
- Anping Yang (ORCID: https://orcid.org/0000-0002-4886-3185)
- Shengru Liang (ORCID: https://orcid.org/0000-0002-8658-8858)
- Yuxin Jin (ORCID: https://orcid.org/0000-0001-8611-9739)
- Wencheng Zhang (ORCID: https://orcid.org/0009-0008-6956-7538)
- Bin Gao (ORCID: https://orcid.org/0000-0003-2282-015X)
- Xinwen Yu (ORCID: https://orcid.org/0000-0003-0733-8074)
- Sun Fei (ORCID: https://orcid.org/0000-0002-3668-9108)
- Li Tian
- Guohong Zhao (ORCID: https://orcid.org/0000-0002-0313-1220)
Institutions
- Tang Du Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Postgraduate Medicine
- Published
- 2025-10-02
- DOI
- https://doi.org/10.1080/00325481.2025.2570106
- Citations
- 1
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.29