Risk factors and predictive modeling of intraoperative hypothermia in laparoscopic surgery patients

Inadvertent intra-operative hypothermia (< 36 °C) is frequent during laparoscopic surgery and worsens postoperative outcomes. Reliable risk-prediction tools for this setting are still lacking. We retrospectively analysed 207 adults who underwent laparoscopic procedures at a single hospital (June 2021 – June 2024). Core temperature was recorded nasopharyngeally every 15 min. Hypothermia was defined as any intra-operative value < 36 °C. Univariable tests and multivariable logistic regression identified independent predictors; coefficients were converted into a weighted risk score. Model discrimination (AUC) and calibration (Hosmer–Lemeshow test, calibration plot) were assessed with 1 000-bootstrap internal validation. Hypothermia occurred in 110 patients (53%). Five variables remained independently associated with risk: body-mass index ≤ 23 kg m⁻², baseline core temperature ≤ 36.1 °C, operating-room temperature ≤ 22 °C, surgical duration ≥ 120 min, and pre-operative systolic blood pressure > 130 mmHg (all P < 0.05). The resulting five-item score (0–12 points) showed good discrimination (optimism-corrected AUC 0.80, 95% CI 0.74–0.87) and adequate calibration (Hosmer–Lemeshow P = 0.10; Brier = 0.18). A cut-off ≥ 3 points identified high-risk patients with 68% sensitivity and 90% specificity. Low BMI, low baseline temperature, cool theatre environment, prolonged surgery and hypertension jointly heighten hypothermia risk during laparoscopy. The simple five-item score enables rapid pre-operative stratification and may guide targeted warming strategies. External multicentre validation is warranted.

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Journal
BMC Surgery
Published
2025-10-03
DOI
https://doi.org/10.1186/s12893-025-03186-z
Primary Topic
Thermal Regulation in Medicine
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article
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article

Risk factors and predictive modeling of intraoperative hypothermia in laparoscopic surgery patients

H. W. Sheng, Yan Cheng
BMC Surgery
Thermal Regulation in Medicine
article

Risk factors and predictive modeling of intraoperative hypothermia in laparoscopic surgery patients

H. W. Sheng, Yan Cheng
article en

Abstract

Inadvertent intra-operative hypothermia (< 36 °C) is frequent during laparoscopic surgery and worsens postoperative outcomes. Reliable risk-prediction tools for this setting are still lacking. We retrospectively analysed 207 adults who underwent laparoscopic procedures at a single hospital (June 2021 – June 2024). Core temperature was recorded nasopharyngeally every 15 min. Hypothermia was defined as any intra-operative value < 36 °C. Univariable tests and multivariable logistic regression identified independent predictors; coefficients were converted into a weighted risk score. Model discrimination (AUC) and calibration (Hosmer–Lemeshow test, calibration plot) were assessed with 1 000-bootstrap internal validation. Hypothermia occurred in 110 patients (53%). Five variables remained independently associated with risk: body-mass index ≤ 23 kg m⁻², baseline core temperature ≤ 36.1 °C, operating-room temperature ≤ 22 °C, surgical duration ≥ 120 min, and pre-operative systolic blood pressure > 130 mmHg (all P < 0.05). The resulting five-item score (0–12 points) showed good discrimination (optimism-corrected AUC 0.80, 95% CI 0.74–0.87) and adequate calibration (Hosmer–Lemeshow P = 0.10; Brier = 0.18). A cut-off ≥ 3 points identified high-risk patients with 68% sensitivity and 90% specificity. Low BMI, low baseline temperature, cool theatre environment, prolonged surgery and hypertension jointly heighten hypothermia risk during laparoscopy. The simple five-item score enables rapid pre-operative stratification and may guide targeted warming strategies. External multicentre validation is warranted.

BMC SurgeryVol. 25(1)
Third People's Hospital of Hefei (CN)
Openalex Percentile: Top 68%
Thermal Regulation in Medicine
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Risk factors and predictive modeling of intraoperative hypothermia in laparoscopic surgery patients — H. W. Sheng, Yan Cheng · BMC Surgery (2025) | TGRS Research Map | TGRS